About MPS

Microphysiological Systems

Aims and Scope

It has been increasingly realized that the conventional planar cell cultures and the animals do not necessarily reproduce human physiology in vitro due to their limited structural and functional complexity and the genetic difference, respectively, oftentimes leading to inaccurate prediction of drug, chemical, and toxin effects as well as biased outcomes of biological investigations. Miniaturized physiological systems are therefore proposed as alternative platforms that are anticipated to bridge the gap between currently available models and the human body. The Journal Microphysiological Systems (Microphysiol Syst; MPS; Online ISSN 2616-275X) aims to provide latest insights and updates on the developments of in vitro tissue and organ models that can be used for applications ranging from biological studies to areas such as regenerative engineering, organs-on-chips, pharmaceutical screening, nanomedicine, and environmental toxicology.

Microphysiological Systems coverage includes but is not limited to:

  • Scaffolding approaches for organoid cultures
  • Biofabrication strategies based on e.g. microengineering and bioprinting for generating complex, functional organoids
  • Advanced microfluidics and on-chip technologies for integrating dynamic microenvironments
  • Multi-organ systems that enable inter-tissue interactions
  • Pharmacodynamics and pharmacokinetics studies
  • Scaling laws that translate the human system into the miniaturized systems
  • Computational methods for guiding model designs
  • Personalized medicine using stem cells
  • Disease modeling
  • Bioanalysis methods for monitoring organoid responses
  • Big data analyses of microphysiological systems


Microphysiological Systems is indexed and covered by

Information for Authors

MPS is a member of Committee on Publication Ethics (COPE) and it follows the Committee on Publication Ethics (COPE)'s guidelines and the ICMJE recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journal.

Manuscripts submitted must be the original work of the author(s) and must not be published previously or under consideration for publication elsewhere.

Submission Turnaround Time

  • In-house review: 1-3 weeks
  • External peer review: 1-3 months
  • Publication Ahead of Print: within 1 month after being accepted
  • Formal publication: within 1-3 months after being accepted. Original Articles are listed as priority.

Open Access Statement

Microphysiological Systems is a peer reviewed, open access journal. All content of the journal is published under the Creative Commons Attribution-NonCommercial- NoDerivatives 4.0 International License (CC BY-NC-ND 4.0). All articles published open access will be immediately and permanently free for all to read, download, copy and distribute as defined by the applied license.

Free access and usage
Permitted third party reuse is defined by the CC BY-NC-ND 4.0 license. This license allows users to copy and distribute the article, provided:

  • this is not done for commercial purposes and further does not permit distribution of the Article if it is changed or edited in any way.
  • the user gives appropriate credit (with a link to the formal publication through the relevant DOI) and provides a link to the license but not in an any way implying that the licensor is endorsing the user or the use of the work.
  • no derivatives including remix, transform, or build upon the material was allowed for distribution.
The full details of the license are available at https://creativecommons.org/licenses/by-nc-nd/4.0/


For open access publishing, this journal uses an exclusive licensing agreement. Authors will transfer copyright to MPS, but will have the right to share their article in the same way permitted to third parties under the relevant user license, as well as certain scholarly usage rights.

For any inquiry/special circumstance on the copyright, commercial usage or adaptation of MPS articles, please contact: permissions@amegroups.com

For reprint order, please contact: sales@amegroups.com

Support for Authors to Comply with Funding Body Mandates

We work with authors of research articles supported by funding bodies with open access mandates to ensure that authors can meet their funders’ requirements for public access to research results.

In addition, we offer further support for authors who are required to comply with funding body mandates, including but not limited to:

Editorial Office

Email: mps@amegroups.com

Publisher Information

MPS is published by AME Publishing Company.
Address: Flat/RM C 16F, Kings Wing Plaza 1, NO. 3 on Kwan Street, Shatin, NT, Hong Kong, China.

Updated on March 21, 2024